Home > Research > NIBIB Intramural Labs > Staff Page: Xiaoyuan Chen

E-mail this page

Dongyu Gu, M.S. Special Volunteer Radiochemistry Group PET Radiochemistry Group Building 10, Room 1C401 Tel: 301-451-3534 E-mail: gud2@mail.nih.gov

Photo by JudeGustafson

Biography

Dongyu Gu graduated from the Graduate School of Chinese Academy of Sciences, Beijing, China, with an advanced degree in organic chemistry. She is now a first year Ph.D. student in Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences working on separation science and analytical chemistry. She joined the PET Radiochemistry Group as a special volunteer to identify and quantify radiotracer metabolites.

Back to Top

Research

Dongyu Gu’s recent research focuses on the identification and quantitation of metabolites of a series of RGD peptide-based radiotracers in vitro and in vivo by LC/MS. The inherent inability of PET to differentiate between a parent compound and its metabolites confounds the interpretion of images and may impact the identification of pathologically induced biochemical changes under investigation. Understanding the metabolic fate of radiopharmaceutical probes is essential for accurate analysis and interpretation of PET measurements.

Selected Publications

Yang Y, Huang Y, Gu D, Yili A, Sabir G, Aisa HA.Separation and purification of three flavonoids from helichrysum arenarium (L.) moench by HSCCC. Chromatographia, 69:963-967, 2009.

Gu D, Yang Y, Zhong J, Aisa HA, Zhang T. High-speed countercurrent chromatography combined with column chromatography for isolation of Methyllycaconitine from delphinium pseudocyanthum. Chromatographia, 66:949, 2007.